30 years of immunomodulation by intravenous immunoglobulin
نویسندگان
چکیده
منابع مشابه
Uses of intravenous immunoglobulin
Adjuvant high dose IVIgs are being used increasingly in a range of immune-mediated and auto-immune diseases. Although numerous immunomodulatory mechanisms have been suggested, the exact mechanisms of action are poorly understood. The efficacy of IVIg in certain diseases has been proven in clinical trials, in so far as IVIg is approved as the therapy of choice for Kawasaki syndrome and idiopathi...
متن کاملIntravenous Immunoglobulin and Immunomodulation of B-Cell – in vitro and in vivo Effects
Intravenous immunoglobulin (IVIG) is used as replacement therapy in patients with antibody deficiencies and at higher dosages in immune-mediated disorders. Although different mechanisms have been described in vitro, the in vivo immunomodulatory effects of IVIG are poorly understood. Different studies have suggested that IVIG modulates B-cell functions as activation, proliferation, and apoptosis...
متن کاملClinical Application and Functional Mechanisms of Intravenous Immunoglobulin: an Overview
Previous, Intravenous Immunoglobulin (IVIG) has been used for treatment of patients with immunodeficiency. However, recent studies have shown that IVIG is a suitable approach for treatment of inflammatory and autoimmune diseases. Although the exact mechanism of IVIG action is not well known, recent findings have demonstrated that IVIG impacts on expression and function of FC receptors of immuno...
متن کاملApplications of intravenous immunoglobulin.
Intravenous immunoglobulin (IV Ig) preparations allow large amounts of IgG to be administered rapidly and painlessly. Currently, there are a number of IV IgG preparations available which differ in their manufacturing methods. However, all the licensed preparations are associated with a low incidence of adverse reactions on administration. They are used mainly for IgG replacement therapy in pati...
متن کاملEnergized by Circulation Research over 30 years.
As a medical student of Okayama University in Japan in the early 1960s, I was very impressed by the well-designed cardiac pump function after watching and touching beating hearts in situ in canine open-chest experiments and learning about the heart in physiology classes. This definitely motivated me to learn more about cardiac function throughout my education. My dream in those days was to comb...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Immunotherapy
سال: 2012
ISSN: 1750-743X,1750-7448
DOI: 10.2217/imt.12.60